Cast & Crew

Starring

• Teri Hatcher - Susan Mayer
• Felicity Huffman - Lynette Scavo
• Marcia Cross - Bree Hodge, formerly Bree Van De Kamp
• Eva Longoria - Gabrielle Solis Marquez
• Nicolette Sheridan - Edie Britt
• Ricardo Antonio Chavira - Carlos Solis
• Andrea Bowen - Julie Mayer
• Doug Savant - Tom Scavo
• Kyle MacLachlan - Orson Hodge
• Brenda Strong - Mary Alice Young
• James Denton - Mike Delfino

Also starring

• Shawn Pyfrom - Andrew Van De Kamp (Season 2–) recurring previously
• Joy Lauren - Danielle Van De Kamp (Season 2–) recurring previously
• Josh Henderson - Austin McCann (Season 3–)
• Brent Kinsman - Preston Scavo (Season 2–) recurring previously
• Shane Kinsman - Porter Scavo (Season 2–) recurring previously
• Zane Huett - Parker Scavo (Season 2–) recurring previously

Formerly starring

• Steven Culp - Rex Van De Kamp (Season 1) recurring afterwards
• Alfre Woodard - Betty Applewhite (Season 2) recurring previously
• Mark Moses - Paul Young (Seasons 1−2) recurring afterwards
• Cody Kasch - Zach Young (Seasons 1−2) recurring afterwards
• Jesse Metcalfe - John Rowland (Season 1) recurring afterwards
• Richard Burgi - Karl Mayer (Season 1−2) recurring otherwise
• Mehcad Brooks - Matthew Applewhite (Season 2) recurring previously
• Page Kennedy - Caleb Applewhite #1 (Season 2) credited until ep. 30
• NaShawn Kearse - Caleb Applewhite #2 (Season 2) first appearance in ep. 31
• Roger Bart - George Williams (Season 2) recurring otherwise

Recurring

• Steven Culp - Rex Van De Kamp (Season 2−) starring previously
• Jesse Metcalfe - John Rowland (Season 2−) starring previously
• Roger Bart - George Williams (Season 2) starring previously
• Richard Burgi - Karl Mayer (Season 3−) starring previously
• Mark Moses - Paul Young (Season 3−) starring previously
• Cody Kasch - Zach Young (Season 3−) starring previously
• Harriet Sansom Harris - Felicia Tilman (Seasons 1−2)
• Christine Estabrook - Martha Huber (Season 1)
• Pat Crawford Brown - Ida Greenberg
• Kathryn Joosten - Karen McCluskey
• Ryan Carnes - Justin (Seasons 1−2)
• Conor O'Farrell - Detective Copeland (Season 1)
• Mark L. Taylor - Mr. Steinberg (Season 1)
• Lesley Ann Warren - Sophie Bremmer Flickman (Seasons 1−2)
• Bob Newhart - Morty Flickman (Seasons 1−2)
• Sam Lloyd - Dr. Albert Goldfine
• Bob Gunton - Noah Taylor (Seasons 1−2)
• Lupe Ontiveros - Juanita Solis (Season 1)
• Terry Bozeman - Dr. Craig
• Currie Graham - Ed Ferrara (Season 2-)
• Joely Fisher - Nina Fletcher (Season 2)
• Jay Harrington - Dr. Ron McCready (Season 2)
• Gwendoline Yeo - Xiao-Mei (Seasons 2−3)
• Lee Tergesen - Peter McMillian (Season 2)
• Jeff Doucette - Father Crowley
• Dakin Matthews - Reverend Sikes
• Melinda Page Hamilton - Sister Mary Bernard (Season 2)
• Sharon Lawrence - Maisy Gibbons (Season 1)
• Shirley Knight - Phyllis Van De Kamp (Season 2)
• Lucille Soong - Yao Lin (Season 1)
• Richard Roundtree - Jerry Shaw (Season 1)
• Betty Murphy - Alberta Fromme
• Alejandro Patino - Ralph (Season 2)
• Melinda McGraw - Annabel Foster (Season 1)
• Kurt Fuller - Detective Barton (Season 2−)
• Charlie Babcock - Stu (Season 2)
• Kathryn Harrold - Helen Rowland (Seasons 1−2)
• Nick Chinlund - Detective Sullivan
• Adrian Pasdar - David Bradley (Season 2)
• Dagney Kerr - Nurse Heisel
• Heather Stephens - Kendra Taylor (Season 1)
• Paul Dooley - Addison Prudy (Season 2−)
• Joyce Van Patten - Carol Prudy (Season 2−)
• Marla Sokoloff - Claire (Season 1)
• Carol Mansell - Pat (Season 2−)
• Tanner Maguire - Young Zach (Seasons 1−2)
• Nike Doukas - Natalie Klein (Season 1)
• Kiersten Warren - Nora Huntington (Seasons 2−3)
• Rachel Fox - Kayla Huntington (Season 3−)
• Jill Brennan - Tish Atherton
• Dougray Scott - Ian Hainsworth (Season 3−)
• Laurie Metcalf - Carolyn Bigsby (Season 3)
• Matt Roth - Art Shephard (Season 3)
• Ernie Hudson - Detective Ridley (Season 3−)
• Kathleen York - Monique Pollier (Season 3−)
• Brian Kerwin - Harvey Bigsby (Season 3-)
• Dixie Carter - Gloria Hodge (Season 3−)
• Mark Deklin - Bill Pearce (Season 3)
• Juliette Goglia - Amy Pearce (Season 3)
• Valerie Mahaffey - Alma Hodge (Season 3−)
• Jennifer Dundas - Rebecca Shephard (Season 3)
• Alec Mapa - Vern (Season 2−)
• Kathleen Gati - Maya (Season 3−)