Season 4
September 30th 2007 - May 18th 2008


The main mystery this season is about a family returning to Wisteria Lane, after 12 years away. Katherine Mayfair comes to Wisteria Lane from Chicago with her (new) husband, Adam, and her daughter, Dylan. Dylan used to be Julie's best friend, although Dylan now doesn't remember anything about Julie, or living in Wisteria Lane at all. Katherine is happily reunited with her old friend Susan, although she doesn't get along at all with Bree. Katherine claims that she returned to Wisteria Lane to take care of her ill aunt Lillian, but private conversations between Katherine and her husband suggest otherwise.

Susan's story
Susan Delfino is finally married to Mike Delfino, but has difficulty in settling down as she fears Mike isn't as happy as he should be. When finding out there is a possibility she has menopause, Susan grows emotional and turns her relationship with Mike to a blatant line. When Adam Mayfair, a gynecologist, tells Susan she is pregnant, she (along with Mike) is overjoyed. Susan's daughter Julie has difficulty in living with Mike, as both of them clash with their separate opinions. Susan is later told by both Mike and Julie to choose between one of the two, and stick to the decision. Susan asks Bree to see her gynecologist after she says it feels funny seeing Adam, as he's Katherine's husband. Susan is later sexually violated, and her relationship with Bree becomes corrupted. Susan then discovers that Mike is addicted to drugs once again. Following the revelation, she meets Barrett who is revealed as the drug dealer Mike is getting his drugs from. Believing Barrett to be a good boy for her daughter Julie, she sets the two up only to find out Barrett is a drug dealer and throws him out of the house.
She then sends Mike to rehab for 30 days in which she is forbidden to make contact with him. Therefore, she becomes dependent on Bree (Marcia Cross) who has been staying with Susan while her house is re-built.

Lynette's story
Lynette Scavo is sick with cancer and is hiding the fact by wearing a wig similar to her hair. No one knows except Tom, her mother Stella, who is staying with the family, and Lynette's sisters. Tom and Stella attempt to convince her that things would be so much easier for her if she told everyone the truth. After losing energy and suffering from fatigue and nausea, she tells everyone the truth. Lynette's cancer disturbs Gabrielle and makes her uncomfortable, as her father had died of cancer. Lynette's issues with Stella continue, meanwhile Stella bakes pot into brownies to get Lynette's nausea settled and her energy back. Despite Lynette's illness, she still wants to seem attractive to Tom and she buys a wig to turn him on but he doesn't feel like making love to a sick person, and Tom's feelings about Lynette's disease come forth. Katherine Mayfair gets on Lynette's nerves when Katherine wants to run for President of their neighborhood and get rid of unsightly things on Wisteria Lane, and Lynette runs against her; she loses the race because of Susan. She later forgave Susan. After killing an opossum that came into their home uninvited (she was really mad at cancer) her doctor pays a house call to let Lynette and her family know that her cancer is gone. Now, the last uninvited thing she needs to rid her house of is her mother. Following a conversation between her three daughters which she overhears, Stella is brokenhearted and leaves without warning. A few days later after constant searching, Lynette arrives home to find her stepfather in her kitchen. Devising a plan to get Stella to return home, Lynette and Glenn (her stepfather) go to the park where Stella asked Glenn to meet her and give her money. After Stella catches Lynette, she appears angry that she was set up. In the mess, Glen reveals to Lynette that he didn't leave Stella because she cheated on him, but because he is gay. The situation ends with Stella agreeing to live at Glenn's home, due to a spare bedroom in the home. Lynette's family hides in Karen McCluskey's house during the tornado. However, her house gets destroyed while Lynette and Karen are not inside the house during the tornado, and the two escape the collapse. It is revealed that Ida Greenberg got all of Lynette's family under the stairs and they survived. Ida, however, died as there was not enough room under the stairs. She had to sit in a corner, and was killed when the house collapsed in.

Bree's Story
Bree Hodge is pretending to be pregnant with her daughter Danielle's baby so she can adopt and raise the baby without anyone even knowing that it's Danielle's. She faces some obstacles along the way, with an elderly woman wanting to touch her belly and a BBQ fork being stabbed into her false belly. Orson tells her that he thinks they should throw in the towel, but Bree refuses to do that. Bree's ex-mother-in-law finds out about Bree's faux pregnancy but promises to keep her secret. Danielle goes into labor at Bob and Lee's Halloween party while she's dressed as Bree, and Adam Mayfair, who also knows her secret and promises to not tell anyone, delivers little Benjamin Hodge. Danielle decides to let Bree raise her baby and leaves Fairview, probably to go to college. Bree then gets Benjamin circumcised against Orson's wishes. Following the circumcision, Bree attempts to raise Benjamin in what is known as a family bed, where she has Benjamin sleep in bed with Orson and herself. After a confrontation at the dinner table, Orson begins sleeping on the couch while Andrew moves out having been labelled a "mistake". Shortly after, Bree goes to visit Andrew only to finally realize that her son has become a man and matured greatly.

Gabrielle's Story
Gabrielle Lang is in an unhappy marriage with Victor. She wants to get back with Carlos, but, although he wants her as well, he feels responsible for Edie. Edie Britt faked a suicide attempt to win Carlos back. She discovers his hidden assets in an offshore bank account and uses this to blackmail him into continuing their relationship. Edie gets crabs from a tanning bed that she transmits to Carlos, which he gives to Gabrielle, who eventually gives them to Victor. Edie puts the pieces together and realizes what's going on. She hires a private investigator and the PI finds Carlos with Gabrielle in a lip lock. Edie shows these pictures to Victor in hopes of him doing something awful to Carlos. On a boat trip out to sea Victor confronts Gabrielle about the affair and pulls a black bag out of a cabinet. Fearing the bag contained a gun, Gabrielle hit him over the head with an oar, knocking him overboard. She meets up with Carlos back on shore and the two realize there was no weapon in the bag - only a sweater. They go back into the water and find Victor and pull him back onto the boat. Victor and Carlos then get into a fist fight. Just as Victor is about to stab Carlos with a knife, Gabrielle, once again, knocks him overboard with an oar. This time, Victor is nowhere to be found. Gabrielle and Carlos assume Victor is dead and return to shore and send the boat back into the ocean by itself, attempting to make Victor's possible murder appear as accidental - and not involving his wife or Carlos. Two detectives appear at Gabrielle's home questioning her about Victor's whereabouts and following a conversation with Carlos, and an "anonymous" phone call by Edie, Victor is found unconscious on shore and brought to the hospital. Leaving Carlos drugged at her home, Gabrielle arrives at the hospital with the two detectives only for Victor to reveal he remembers nothing. However, after leading the detectives out, Victor reveals he does remember everything, but does not reveal what he will do with the information. He is eventually killed by a fence picket shoved through his stomach during the tornado which had hit Wisteria Lane.
Gabrielle finds out at Victor's funeral that she will not be getting a cent from his will because he knew about the affair. Having gone blind and losing all his offshore money, Carlos did not tell Gabrielle about his blindness